
5.0 Borderlanders – Ozarks

5.1 Pacific & Stanton
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- Meramec Caverns
- Jesse James Museum

5.2 Cuba & Fanning
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- Cuba – Mural City (population: 3,000)
- Wagon Wheel Motel
- Phillips 66 Station
- Murals of Cuba
- Bob’s Gasoline Alley
- Fanning – World’s Second Largest Rocking Chair
- Cuba – Mural City (population: 3,000)

5.3 Rolla & Devils Elbow
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- Rolla (population: 20,000) – Totem Pole Trading Post
- Devils Elbow
- Devils Elbow
- Hooker Cut
- Hazelgreen – Gasconade River Bridge

5.4 Lebanon
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- Lebanon (population: 10,000)
- Munger Moss Motel
- Wrinks Market
- Marshfield (population: 7,000) – Hubble Telescope Replica
- Lebanon (population: 10,000)

5.5 Springfield, Missouri
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- Population: 170,000
- Birthplace of Route 66
- Queen City of the Ozarks
- Rest Haven Court
- Original Steak ‘n Shake
- Mudhouse Coffee
- Park Central Square
- Gillioz Theatre


5.6 Paris Springs & Spencer
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- Paris Springs – Sinclair Station
- Spencer – Spencer Garage

5.7 Carthage & Joplin
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- Carthage (population: 15,000)
- Red Oak II
- Boots Motel
- Jasper County Courthouse
- 66 Drive-In
- Webb City (population: 13,000)
- Trolley Car Trestle Remains
- Bradbury Bishop Deli
- Route 66 Visitors Center (former station)
- Route 66 Movie Theater
- Joplin
- Joplin Union Depot (abandoned)
- Fox Theatre
- Route 66 Mural Park
- Bonnie and Clyde Garage Apartment
- Woody’s Wood-Fire Pizza
- Carthage (population: 15,000)

5.8 Kansas – Kansas Route 66
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- Galena
- Cars on the Route/old Kan-O-Tex Service Station & Diner
- Riverton
- Eisler Brothers General Store
- Marsh Rainbow Arch Bridge
- Baxter Springs
- Baxter Springs Independent Oil and Gas Service Station
- Galena